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Boswellia Serrata


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Boswellia serrata with AKBA

5-lipoxygenase (5-LOX) is a member of the lipoxygenase family of enzymes. It transforms fatty acids into leukotrienes. Excess levels of the enzyme 5-LOX sets in motion inflammatory responses that have been linked to common effects in aging individuals.1-5

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Normal aging results in higher-than-desired levels of 5-LOX.
The typical American diet adds to the danger. Foods rich in omega-6 fatty acids like red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger overproduction of arachidonic acid. In response to high levels of arachidonic acid, the body produces the 5-LOX enzyme.
5-LOX breaks down arachidonic acid to pro-inflammatory compounds like leukotriene B4,6 a molecule that mediates attacks to joints, arterial walls, and other tissues. 5-LOX itself facilitates undesirable cell division changes.7,8

The good news is that an extract of the Indian plant Boswellia serrata has been shown to neutralize 5-LOX. Used for centuries to help with inflammatory factors, boswellia acts as a natural 5-LOX inhibitor, intervening at the cellular level to block its unwanted effects. Confirmatory data reveal that a compound contained in boswellia called AKBA (3-O-acetyl-11-keto-ß-boswellic acid)9,10 is the key to its beneficial action.


1 lb, 5 lbs

Supplement Facts

Serving Size 1 gram
Amount Per Serving

(Boswellia serrata) extract (gum resin) [std. to 10% 3-O-acetyl-11-keto-ß-boswellic acid (AKBA) 100 mg]

Other ingredients: None


Dosage and Use
Take one gram daily, before lunch and dinner, or as recommended by a healthcare practitioner.


  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

*These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure or prevent any disease or health condition.


  • Neurobiol Aging. 2007 Sep;28(9):1457-62.
  • Cardiovasc Psychiatry Neurol. 2009;2009:174657.
  • Free Radic Biol Med. 2009 Jul 1;47(1):62-71.
  • Rejuvenation Res. 2009 Feb;12(1):15-24.
  • Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):315-9.
  • Curr Opin Investig Drugs. 2009 Nov;10(11):1163-72.
  • Carcinogenesis. 2006 Sep;27(9):1902-8.
  • Clin Cancer Res. 2005 Mar 1;11(5):2089-96.
  • Wien Med Wochenschr. 2002;152(15-16):373-8.
  • J Ethnopharmacol. 2006 Sep 19;107(2):249-53.

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