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Astragalus Root

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Astragalus root

Why is astragalus root an anti-aging herbal remedy? The anti-aging effect of astragalus root can be attributed to a particular chemical that activates the enzyme telomerase (hTERT).
Think of your DNA like a shoelace, and your telomeres are the plastic caps at the end, which keep your shoelaces from unraveling. The telomeres help protect your DNA during the replication process. When you age, the telomeres shorten, which increases the lifespan of your DNA. The telomerase will protect the telomeres by increasing their length. Telomerase is often deactivated in adult cells; however, telomerase is active in sperm and egg cells, immune cells, and malignant cancer cells. The activation of telomerase can also stimulate additional telomere production.

It also contains other active constituents such as astragalosides, saponins, flavonoids, beta-sitosterol, selenium, and polysaccharides.

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The most notable polysaccharides in astragalus include astragaloside IV, calycosin, and formononetin, which help reduce inflammation and improve immunity. By nature, astragalus has a warming effect and it is sweet tasting.

The following are a few of the best health benefits of astragalus root extract:

1. Immune support
Most notably, the astragaloside IV, calycosin, and formononetin help activate pathways and other genes, which help with immune cell activity. Studies have shown that astragalus root can stimulate the immune system in several ways by improving T cell activity, enhancing the phagocytic activity of macrophages and monocytes, increasing natural killer cell activity, and increasing the potency of the herb’s other antiviral properties.

2. Upper respiratory infections
Astragalus root is considered an effective treatment for acute and chronic bronchitis by strengthening weakened lungs and preventing upper respiratory infections that trigger asthma. The astragaloside, saponins, and flavonoids found in astragalus are thought to be involved to treat and prevent upper respiratory infections such as asthma, bronchitis, tracheitis, laryngitis, sore throats, and the common cold.

3. Chronic hepatitis
Chronic hepatitis is liver inflammation that lasts a minimum of six months; it is commonly caused by hepatitis B or C viruses, as well as certain drugs. A study published in the Chinese Journal of Integrated Traditional and Western Medicine in 2000 found that a supplementation with astragalus root could effectively treat liver fibrosis of chronic hepatitis B patients. Another study published in the Chinese Journal of Hepatology in 2005 found that injecting an astragalus solution could inhibit experimental hepatic fibrogenesis possibly due to its antioxidant activity.

4. Diabetes
Astragalus root is considered an effective remedy for diabetics since it exhibits improved blood sugar control. The polysaccharides in astragalus are thought to benefit those with diabetes. In particular, the active polysaccharide component of astragalus root extract is called astragalus polysaccharide (APS).
In an eight-week rat study published in the journal Acta Pharmacologica Sinica, researchers found that APS extract reduced blood glucose levels and improved insulin sensitivity by activating the enzyme AMP-activated protein kinase (AMPK).

Precautions:
Although there are many astragalus health benefits, there are a few side effects or warnings linked with the herb. The following are some side effects or warnings linked with astragalus root:

  • Astragalus should not be used if you have a fever.
  • Caution should be implemented as astragalus may increase the risk of bleeding in those with bleeding disorders.
  • Caution should also be used in people with high blood pressure, neurological disorders, skin conditions, musculoskeletal disorders, and gastrointestinal conditions.
  • Some holistic health practitioners avoid recommending the long-term use of a single adaptogenic herb. Astragalus should be taken in rotation with other adaptogens.
  • It is also possible that the side effects associated with astragalus root are not well understood since it is often used in combination with other herbs.
WeightN/A
Weight

1 lb, 5 lbs

Nutrition Facts

Nutrition Facts 100 grams
Amount Per Serving

Calories 377
Total Fat 0g
Saturated Fat 0g
Trans Fat 0g
Cholesterol 0mg
Sodium 41mg
Potassium 0mg
Total Carbohydrate 83g
Dietary Fiber 41g
Sugars 0g Added 0 sugar
Protein 0g
Vitamin A 0 IU
Vitamin D 0 mcg
Calcium 41 mg
Iron 0 mg
Vitamin C 0 mg

*Percent Daily Values are based on a 2000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.

Ingredients: Organic Astragalus powder

References

Murray, M., M.D., et al, The Encyclopedia of Natural Medicine (New York: Atria Paperback, 2012), 180.
Balch, J., et al., Prescription for Natural Cures: A Self-Care Guide for Treating Health Problems with Natural Remedies Including Diet, Nutrition, Supplements, and Other Holistic Methods (Hoboken: John Wiley & Sons, Inc., 2004), 60, 123, 128.
Bernardes de Jesus, B., et al., “The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence,” Aging Cell, 2011, 10(4): 604-621, doi: 10.1111/j.1474-9726.2011.00700.x.
Chen, H.W., “A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study,” Clinical and Investigative Medicine, 2012; 35(1): E1-11.
Zou, F., et al., “Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK,” Acta Pharmacologica Sinica, 2009; 30(12): 1607-1615, doi: 10.1038/aps.2009.168.
Rakel, D., et al., Integrative Medicine: Third Edition (Philadelphia: Elsevier Saunders, 2012), 150-151, 179.
Zhou, X., et al., “[Study on the inhibitive effect of Astragalus injection solution on hepatic fibrosis in rats],” Chinese Journal of Hepatology, 2005; 13(8): 575-578.
Chen, H., et al., “[Comparison on efficacy in treating liver fibrosis of chronic hepatitis B between Astragalus Polygonum anti-fibrosis decoction and jinshuibao capsule],” Chinese Journal of Integrated Traditional and Western Medicine, 2000; 20(4): 255-257.
Meininger, K., “Dosage for Astragalus Root,” Livestrong.com, August 27, 2013; http://www.livestrong.com/article/445773-astragalus-root-herb-dosage/.
“Astragalus (Astragalus membranaceus),” Clark’s Nutrition & Foods Market web site; http://www.clarksnutrition.com/ns/DisplayMonograph.asp?storeID=2691b1fe187d41acb869a85ca5957a0a&DocID=bottomline-astragalus#DOSING, last accessed January 4, 2016.
“Astragalus,” National Center for Complementary and Integrative Health web site; https://nccih.nih.gov/health/astragalus, last accessed January 4, 2016.
“Astragalus,” Weil web site; http://www.drweil.com/drw/u/REM00002/Astragalus-Dr-Weils-Herbal-Remedies.html, last accessed January 4, 2016.
“Benefits of Astragalus Root,” Wellness Mama web site; http://wellnessmama.com/15726/astragalus-root-benefits/, last accessed January 4, 2016.
“Astragalus,” WebMD web site; http://www.webmd.com/vitamins-supplements/ingredientmono-963-astragalus.aspx?activeingredientid=963&activeingredientname=astragalus, last accessed January 4, 2015.

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